Azure Synthetics Azure Synthetics Research peptides, clearly documented.
CJC-1295 with DAC

GH-axis research

CJC-1295 with DAC

Lyophilized endocrine-signaling research peptide for systems review

CJC-1295 with DAC is a longer-acting GHRH analog studied for extended GH-axis signaling and albumin-binding pharmacology.

价格范围:49.99 $ 至 212.99 $
98.6%-99.2% Lyophilized powder 5 mg
Available documentation

Support can confirm any currently available COAs or batch documentation for this product.

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仅供实验室研究使用。不适用于人类或兽医用途。并非旨在诊断、治疗、治愈、减轻或预防疾病。

存储

Keep sealed, cold, dry, and protected from heat swings. Confirm product-specific storage on arrival.

Shipping notes

Packed for transit stability with order support available for warm-weather routes.

Batch reference

Batch-linked certificate support is available through the documentation desk.

研究背景

CJC-1295 with DAC 研究资料

CJC-1295 with DAC is a longer-acting GHRH analog designed to extend exposure through drug-affinity-complex chemistry and albumin binding. Research examines pharmacokinetics, prolonged GH and IGF-1 marker changes, pituitary signaling, and how sustained activity differs from shorter GHRH analogs. It is distinct from CJC-1295 No DAC, which is used for shorter pulse-pattern comparisons, and from ipamorelin or GHRP compounds, which signal through the ghrelin receptor. This version is most relevant when half-life extension is central to the study design. Published pharmacology for named investigational material does not independently verify the sequence, purity, or performance of a catalog batch.

Molecular class

DAC-modified GHRH analog

Sequence / composition

A substituted GHRH 1-29-style peptide linked to a Drug Affinity Complex designed for albumin association.

Research design note

The DAC attachment, rather than the name alone, distinguishes the expected exposure profile from a no-DAC construct.

拟议机制

A GHRH analog containing a drug-affinity-complex group designed to form a covalent bond with serum albumin. Albumin binding reduces clearance and prolongs GHRH-receptor stimulation, increasing GH secretion and downstream IGF-1.

研究中报告的作用

  • Healthy-adult studies reported dose-dependent increases in GH lasting several days and increases in IGF-1 lasting approximately one to two weeks after studied exposures.
  • Repeated exposure in pharmacology studies produced sustained elevation of GH and IGF-1 without eliminating pulsatile secretion.
  • Reported observations included injection-site reactions and endocrine changes expected from prolonged GH-axis stimulation.

常见研究终点

Albumin binding, half-life, GHRH receptor activity, GH pulse pattern, integrated GH exposure, IGF-1, glucose, insulin, binding proteins, pharmacokinetics, and adverse events.

证据与局限

Controlled human pharmacology exists for the original investigational CJC-1295 with DAC. Product sequence and DAC chemistry must match before those data are considered relevant.

External reading

Literature for context—not product proof.

Third-party sources describe their own research materials and methods. They do not validate a specific Azure catalog batch.

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